General Cell Based Assays
Eurofins Discoverx cAMP Hunter eXpress ADCYAP1R1 (PAC1) CHO-K1 GPCR Assay, 10pl Kit. (95-0064E2CP2L)
The cAMP Hunter ADCYAP1R1 (PAC1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PACAP) based activation of ADCYAP1R1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADCYAP1R1, a naturally Gs coupled GPCR. Upon activation of ADCYAP1R1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human ADRA2C β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human ADRA2C β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADRA2C (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Cerivastatin sodium, HMG-CoA reductase inhibitor, 5MG
MW 481.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor (Ki = 13 nM). Shows higher potency than Lovastatin (ab120614). Enantiomerically pure pyridine derivative. Reduces plasma cholesterol levels in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Bioassay Systems EnzyChrom™ Acetylcholine Assay Kit. For quantitative determination of acetylcholine and evaluation of drug effects on acetylcholine metabolism.
For quantitative determination of acetylcholine and evaluation of drug effects on acetylcholine metabolism. Key Features: Use 20 µL samples. Linear detection range: colorimetric assay 10 to 200 µM, fluorimetric assay 0.4 to 10 µM acetylcholine. Method: OD570nm, or FL530/585nm. Samples: Serum, plasma, urine, saliva, milk, tissue, and cell culture etc. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: OD, FL: 10, 0.4 µM.
Eurofins Discoverx PathHunter Human IKZF3v1 Degradation Cell-Based Assay Kit (HEK 293)
The PathHunter Human IKZF3v1 Degradation Stable Cell Line Assay (HEK 293) measures pathway activation-induced degradation of IKZF3v1 target protein. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MCHR2 β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human MCHR2 β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure MCHR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Discovery Life Sciences Gentest Human Hepatocytes
Gentest Human Hepatocytes Cryopreserved Plateable Transporter Qualified
Discovery Life Sciences Gentest Cryo White Rabbit Hep
Gentest Cryopreserved New Zealand White Rabbit Hepatocytes Male plateable
Eurofins Discoverx PathHunter eXpress GPR83 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0441E2ACP1M)
The PathHunter GPR83 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR83 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR83 and EA-tagged β-Arrestin-2. Activation of GPR83 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress MTNR1A CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0951E2CP2M)
The PathHunter MTNR1A eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. 2-iodomelatonin) based activation of MTNR1A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MTNR1A and EA-tagged β-Arrestin-2. Activation of MTNR1A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Discovery Life Sciences Gentest Sprague DawlRat Hep
Gentest Sprague Dawley Rat Hepatocytes Cryopreserved Female Suspension